Hair loss resulting in thinning is known as alopecia. When it is related to hormones (androgens) and genetics, it is known as androgenetic alopecia, or more commonly balding. Male pattern alopecia is characterised by a receding hairline and/or hair loss on the top and front of the head.
Male pattern hair loss or baldness is an inherited condition, caused by a genetically determined sensitivity to the effects of dihydrotestosterone, or DHT in some areas of the scalp. DHT is believed to shorten the growth, or anagen, phase of the hair cycle, from a usual duration of 3-6 years to just weeks or months. This causes miniaturisation of the follicles, and producing progressively fewer and finer anagen hairs. The production of DHT is regulated by an enzyme called 5-alpha reductase.
Several genes are involved, accounting for differing age of onset, progression, pattern and severity of hair loss in family members. The susceptibility genes are inherited from both mother and father. Baldness can have a serious psychological impact. Studies have shown that hair loss can be associated with low self esteem, depression, introversion, and feelings of unattractiveness.
Current treatment options include:
Hair transplants. This type of procedure removes tiny plugs of skin, each containing a few hairs, from the back or sides of your scalp. The plugs are then implanted into the bald sections of your scalp. Several transplant sessions may be needed, as hereditary hair loss progresses with time.
Medications approved by the Food and Drug Administration (FDA) to treat hair loss include Minoxidil solution and Finasteride
Minoxidil is an over-the-counter liquid or foam that you rub into your scalp twice daily to grow hair and to prevent further loss. Some people experience some hair regrowth or a slower rate of hair loss or both. It may take 12 weeks for new hair to start growing. Minoxidil is available in a 2 percent solution and in a 5 percent solution. Side effects can include scalp irritation and occasionally unwanted hair growth on the adjacent skin of the forehead or face.
This prescription medication to treat male-pattern baldness is taken daily in pill form. Many men taking finasteride experience a slowing of hair loss, and some may show some new hair growth. Rare side effects of finasteride include diminished sex drive and sexual function.
Alopecia Areata is thought to be an autoimmune condition in which the skin’s own immune system cells attack hairs at the roots, causing the hairs to fall out intact, leaving smooth, bare patches on the scalp or face. In some patients stress, pregnancy, major trauma or illness precedes hair loss. One fifth of patients have a family history of Alopecia Areata. The condition is cyclical and unpredictable, and the hair can grow back or fall out again at any time. With limited hair loss of less than 40%, hair will usually regrow in a few months.
The preferred method of treatment performed by Dr. Pall is an intralesional corticosteroid injection. The corticosteroid fluid is slowly absorbed from the injection site to the local tissue for the maximum effect. The corticosteroid suppresses the T-cell immune attack on the hair follicles.
Another treatment is topical corticosteroids that involve three months of treatments before any hair regrowth can start and often requires maintenance therapy to limit the effects of alopecia.
Systemic steroids are infrequently used to halt the progression of Alopecia Areata.
Immunotherapy treatments use drugs that be irritating and may cause a mild contact dermatitis that stimulates the scalp hair to regrow
A full recovery of lost hair is common using intralesional steroids. The injections are repeated after 3 to 4 weeks depending upon the response.The goal of any therapy is to limit and control Alopecia Areata.
Mesotherapy is an alternative treatment that helps to cure baldness in both males and females by reducing hair loss, promoting hair growth and slowing male pattern baldness. This is done by injecting in the least painful way, nutrient boosters in the scalp with the help of an injection gun to aid in the nourishing and hydration of the scalp. This also includes initiating cell metabolism, eliminating infections and promoting and accelerating hair growth, improving blood circulation in the scalp and strengthening and reviving the hair follicles to help create dense, voluminous, strong, long and healthy tresses. This is a comparatively faster treatment than its counterparts as it helps to gradually restore hormonal balance and neutralizes the effects of DHT hormone leading to accelerated growth of new hair strands.
Mesotherapy brings just the right materials to the exact place where it is needed (around the hair follicle) so that the hair follicle can grow and survive, the excess of DHT (dihydrotestosterone) is neutralised and the blood circulation is stimulated. Mesotherapy for hair loss is used with great success in Europe and the United States. The treatment is virtually painless and safe when done professionally. There is no dressing or local anaesthesia required. After the treatment you can just go back to work.
Platelet Rich Plasma (PRP)
Dr. Pall implements PRP (Platelet Rich Plasma) hair loss treatment, which is an innovative method for the treatment of male & female hair loss. PRP is based on the platelet-rich plasma, an enriched in platelets portion of blood that is easily extracted after special treatment of a small blood sample. It is an effective treatment for hair loss and a booster treatment after hair transplant. This treatment supports various growth factors which promotes cell proliferation and tissue regeneration.